Yvonne Campman

• Role: PhD Candidate, Neurologist in training

My PhD research primarily focuses on interventions for fatigue in Myasthenia Gravis (MG), a chronic antibody-mediated auto-immune disease affecting the neuromuscular junction, characterized by fluctuating weakness and muscle fatigability. A frequent, persistent and disabling symptom of MG is fatigue, present in ± 80% of patients and strongly associated with a lower quality of life. Limited data is available on the treatment of fatigue in MG and the pathophysiology of fatigue in MG is poorly understood. At the moment we are conducting a randomized controlled trial with multiple intervention arms and a one-year follow-up period to evaluate the efficacy of these treatments on fatigue reduction and quality of life improvement (FIT to ACT – MG). In addition, I manage the national MG registry and I have initiated and coordinate two projects that aim to improve the assessment and monitoring of MG symptoms: CAPTURE-MG, which focuses on enhancing MG assessment through video and audio recordings for the development of a digital monitoring application, and MAP-MG, which uses whole-body muscle MRI imaging to better characterize disease activity. My supervisors are Dr. M.R. Tannemaat and Prof. Dr. J.J.G.M. Verschuuren.