Luuk Wieske completed his medical degree (cum laude; with honor) at the University of Amsterdam (UvA), after which he worked as a resident in Neurology in the Onze Lieve Vrouwe Gasthuis in Amsterdam, the Netherlands. During his study and residency, he became interested in field of neuromuscular disorders, infection and inflammation. This led to his PhD project within the department of Intensive Care Medicine and the department of Neurology in the Amsterdam University Medical Centers, location AMC, on the effects of severe systemic inflammation on the neuromuscular system during critical illness. During his PhD, he travelled to London for a research project on nerve excitability. He successfully defended his thesis in 2014 and started his training in Neurology at the Amsterdam University Medical Centers, location AMC. His combined research training and medical specialization are supported by a personal grant from the Netherlands Organization for Health Research and Development (ZonMw–AGIKO grant 2011). In 2020 he registered as a neurologist and started working as a fellow neuromuscular disorders.
Currently, his focus is on biomarker research in chronic inflammatory demyeliniating neuropathy (CIDP). He works as a coordinating investigator for INCbase, an international CIDP registry, and Target to B!, an immunological consortium in the Netherlands studying B-cell related disorders. His ambition is to become an academic neurologist with a focus on neuromuscular disorders and combining patient care with education and (pre–) clinical research.